R4W (p.Arg4Trp) variant of ITGB3 (Integrin beta-3)
R4W (p.Arg4Trp) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
R4W (p.Arg4Trp) variant details
- p.Arg4Trp
- gnomAD 17-47253871-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- MetaLR 0.05
- MetaSVM -0.92
- CADD 22.40
- PolyPhen-2 0.04
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available