P9L (p.Pro9Leu) variant of ITGB3 (Integrin beta-3)
P9L (p.Pro9Leu) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P9L (p.Pro9Leu) variant details
- p.Pro9Leu
- ExAC rs763800456
- TOPMed rs763800456
- gnomAD rs763800456
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- MetaLR 0.04
- MetaSVM -1.04
- CADD 7.22
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available