P5R (p.Pro5Arg) variant of ITGB3 (Integrin beta-3)
P5R (p.Pro5Arg) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P5R (p.Pro5Arg) variant details
- p.Pro5Arg
- TOPMed rs897126842
- gnomAD rs897126842
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- MetaLR 0.03
- MetaSVM -1.09
- CADD 11.50
- PolyPhen-2 0.04
- SIFT 0.26
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available