P5L (p.Pro5Leu) variant of ITGB3 (Integrin beta-3)
P5L (p.Pro5Leu) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P5L (p.Pro5Leu) variant details
- p.Pro5Leu
- TOPMed rs897126842
- gnomAD rs897126842
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- MetaLR 0.03
- MetaSVM -1.10
- CADD 13.50
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the East Asian population (allele frequency 7.7e-05)
- Structural context available