L10V (p.Leu10Val) variant of ITGB3 (Integrin beta-3)
L10V (p.Leu10Val) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- gnomAD rs1489964393
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- MetaLR 0.06
- MetaSVM -1.02
- CADD 13.60
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 4.1e-05)
- Structural context available