G35S (p.Gly35Ser) variant of ITGB3 (Integrin beta-3)
G35S (p.Gly35Ser) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
G35S (p.Gly35Ser) variant details
- p.Gly35Ser
- TOPMed rs1235786723
- gnomAD rs1235786723
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- MetaLR 0.14
- MetaSVM -0.97
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.32
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available