G35D (p.Gly35Asp) variant of ITGB3 (Integrin beta-3)
G35D (p.Gly35Asp) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
G35D (p.Gly35Asp) variant details
- p.Gly35Asp
- gnomAD 17-47274443-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- MetaLR 0.17
- MetaSVM -0.84
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available