G27W (p.Gly27Trp) variant of ITGB3 (Integrin beta-3)
G27W (p.Gly27Trp) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
G27W (p.Gly27Trp) variant details
- p.Gly27Trp
- gnomAD 17-47253940-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- MetaLR 0.10
- MetaSVM -0.96
- CADD 35.00
- PolyPhen-2 0.17
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available