G22S (p.Gly22Ser) variant of ITGB3 (Integrin beta-3)
G22S (p.Gly22Ser) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
G22S (p.Gly22Ser) variant details
- p.Gly22Ser
- gnomAD 17-47253925-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- MetaLR 0.07
- MetaSVM -0.98
- CADD 24.20
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available