G22D (p.Gly22Asp) variant of ITGB3 (Integrin beta-3)
G22D (p.Gly22Asp) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G22D (p.Gly22Asp) variant details
- p.Gly22Asp
- gnomAD rs2064977458
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- MetaLR 0.07
- MetaSVM -1.08
- CADD 22.90
- PolyPhen-2 0.02
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available