G22C (p.Gly22Cys) variant of ITGB3 (Integrin beta-3)
G22C (p.Gly22Cys) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
G22C (p.Gly22Cys) variant details
- p.Gly22Cys
- gnomAD 17-47253925-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- MetaLR 0.05
- MetaSVM -1.12
- CADD 29.30
- PolyPhen-2 0.28
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available