A21S (p.Ala21Ser) variant of ITGB3 (Integrin beta-3)
A21S (p.Ala21Ser) in ITGB3 (Integrin beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 17-47253922-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- MetaLR 0.04
- MetaSVM -1.07
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.67
- Most common in the Finnish in Finland (FIN) population (allele frequency 6e-05)
- Structural context available
- Literature evidence available