Y37D (p.Tyr37Asp) variant of ITGA6 (Integrin alpha-6)
Y37D (p.Tyr37Asp) in ITGA6 (Integrin alpha-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Y37D (p.Tyr37Asp) variant details
- p.Tyr37Asp
- gnomAD 2-172427897-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- CADD 15.10
- PolyPhen-2 0.00
- SIFT 0.94
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available