R35W (p.Arg35Trp) variant of ITGA6 (Integrin alpha-6)
R35W (p.Arg35Trp) in ITGA6 (Integrin alpha-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
R35W (p.Arg35Trp) variant details
- p.Arg35Trp
- TOPMed rs1233010383
- gnomAD rs1233010383
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- CADD 28.50
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available