L9S (p.Leu9Ser) variant of ITGA6 (Integrin alpha-6)
L9S (p.Leu9Ser) in ITGA6 (Integrin alpha-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
L9S (p.Leu9Ser) variant details
- p.Leu9Ser
- gnomAD rs1291296354
- Missense
- Variant Prioritization Score for Impact Estimate 0.57
- CADD 22.90
- PolyPhen-2 0.06
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available