L16F (p.Leu16Phe) variant of ITGA6 (Integrin alpha-6)
L16F (p.Leu16Phe) in ITGA6 (Integrin alpha-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- Ensembl rs767272243
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- CADD 23.80
- PolyPhen-2 0.78
- SIFT 0.17
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available