I34F (p.Ile34Phe) variant of ITGA6 (Integrin alpha-6)
I34F (p.Ile34Phe) in ITGA6 (Integrin alpha-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
I34F (p.Ile34Phe) variant details
- p.Ile34Phe
- TOPMed rs972560376
- gnomAD rs972560376
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- CADD 26.80
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available