W20S (p.Trp20Ser) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
W20S (p.Trp20Ser) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
W20S (p.Trp20Ser) variant details
- p.Trp20Ser
- gnomAD 14-74493833-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.17
- CADD 19.50
- PolyPhen-2 0.06
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available