W20R (p.Trp20Arg) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
W20R (p.Trp20Arg) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
W20R (p.Trp20Arg) variant details
- p.Trp20Arg
- gnomAD 14-74493832-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.10
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available