S8Y (p.Ser8Tyr) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
S8Y (p.Ser8Tyr) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
S8Y (p.Ser8Tyr) variant details
- p.Ser8Tyr
- gnomAD 14-74493797-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.03
- CADD 4.19
- PolyPhen-2 0.06
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available