R24W (p.Arg24Trp) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
R24W (p.Arg24Trp) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
R24W (p.Arg24Trp) variant details
- p.Arg24Trp
- gnomAD rs1207642936
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.32
- CADD 35.00
- PolyPhen-2 0.91
- SIFT 0.03
- Population evidence available
- Structural context available