R22G (p.Arg22Gly) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
R22G (p.Arg22Gly) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R22G (p.Arg22Gly) variant details
- p.Arg22Gly
- cosmic curated COSV53143
- gnomAD rs1226430569
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.14
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.29
- Population evidence available
- Structural context available