P21A (p.Pro21Ala) variant of ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial)
P21A (p.Pro21Ala) in ISCA2 (Iron-sulfur cluster assembly 2 homolog, mitochondrial) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P21A (p.Pro21Ala) variant details
- p.Pro21Ala
- TOPMed rs2086811150
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.06
- CADD 10.90
- PolyPhen-2 0.00
- SIFT 0.54
- Population evidence available
- Structural context available