E32del (p.Glu32del) variant of IRF8 (Interferon regulatory factor 8)

Name: IRF8 E32del (p.Glu32del) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

E32del (p.Glu32del) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.

E32del (p.Glu32del) variant details

rs1567875661
gnomAD 16-85903105-TGAG-
Inframe Deletion
Variant Prioritization Score for Impact Estimate 0.234
CADD 21.70
Most common in the South Asian population (allele frequency 1.2e-05)
Structural context available
Literature evidence available