W60R (p.Trp60Arg) variant of IRF8 (Interferon regulatory factor 8)
W60R (p.Trp60Arg) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
W60R (p.Trp60Arg) variant details
- p.Trp60Arg
- gnomAD 16-85908993-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.834
- REVEL 0.95
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available