T77S (p.Thr77Ser) variant of IRF8 (Interferon regulatory factor 8)
T77S (p.Thr77Ser) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
T77S (p.Thr77Ser) variant details
- p.Thr77Ser
- TOPMed rs922368153
- gnomAD rs922368153
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.60
- CADD 23.70
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available