S21T (p.Ser21Thr) variant of IRF8 (Interferon regulatory factor 8)
S21T (p.Ser21Thr) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
S21T (p.Ser21Thr) variant details
- p.Ser21Thr
- gnomAD 16-85903077-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.35
- CADD 2.79
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available