S21N (p.Ser21Asn) variant of IRF8 (Interferon regulatory factor 8)
S21N (p.Ser21Asn) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S21N (p.Ser21Asn) variant details
- p.Ser21Asn
- gnomAD 16-85903077-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.34
- CADD 1.60
- PolyPhen-2 0.00
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available