S21I (p.Ser21Ile) variant of IRF8 (Interferon regulatory factor 8)
S21I (p.Ser21Ile) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
S21I (p.Ser21Ile) variant details
- p.Ser21Ile
- gnomAD 16-85903077-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.48
- CADD 11.40
- PolyPhen-2 0.12
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available