S21G (p.Ser21Gly) variant of IRF8 (Interferon regulatory factor 8)
S21G (p.Ser21Gly) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
S21G (p.Ser21Gly) variant details
- p.Ser21Gly
- gnomAD 16-85903076-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.27
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available