R8R (p.Arg8Arg) variant of IRF8 (Interferon regulatory factor 8)
R8R (p.Arg8Arg) in IRF8 (Interferon regulatory factor 8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
R8R (p.Arg8Arg) variant details
- p.Arg8Arg
- gnomAD 16-85903037-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.459
- CADD 13.60
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available