R81K (p.Arg81Lys) variant of IRF8 (Interferon regulatory factor 8)

R81K (p.Arg81Lys) in IRF8 (Interferon regulatory factor 8) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance in the context of in a breast cancer sample. The record also includes published literature and structural context.

R81K (p.Arg81Lys) variant details