P24R (p.Pro24Arg) variant of IRF8 (Interferon regulatory factor 8)
P24R (p.Pro24Arg) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
P24R (p.Pro24Arg) variant details
- p.Pro24Arg
- Ensembl rs1904878177
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- REVEL 0.79
- CADD 24.40
- PolyPhen-2 0.70
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available