N87S (p.Asn87Ser) variant of IRF8 (Interferon regulatory factor 8)
N87S (p.Asn87Ser) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
N87S (p.Asn87Ser) variant details
- p.Asn87Ser
- gnomAD 16-85909075-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.815
- REVEL 0.94
- CADD 26.50
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available