N87D (p.Asn87Asp) variant of IRF8 (Interferon regulatory factor 8)
N87D (p.Asn87Asp) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
N87D (p.Asn87Asp) variant details
- p.Asn87Asp
- gnomAD rs1348996824
- Missense
- Variant Prioritization Score for Impact Estimate 0.81
- REVEL 0.93
- CADD 27.50
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available