N49T (p.Asn49Thr) variant of IRF8 (Interferon regulatory factor 8)
N49T (p.Asn49Thr) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
N49T (p.Asn49Thr) variant details
- p.Asn49Thr
- gnomAD 16-85903161-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- REVEL 0.68
- CADD 24.90
- PolyPhen-2 0.56
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available