N30T (p.Asn30Thr) variant of IRF8 (Interferon regulatory factor 8)
N30T (p.Asn30Thr) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
N30T (p.Asn30Thr) variant details
- p.Asn30Thr
- ExAC rs779381872
- gnomAD rs779381872
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.54
- CADD 19.30
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available