M35V (p.Met35Val) variant of IRF8 (Interferon regulatory factor 8)
M35V (p.Met35Val) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
M35V (p.Met35Val) variant details
- p.Met35Val
- gnomAD rs763570356
- Missense
- Variant Prioritization Score for Impact Estimate 0.5
- REVEL 0.61
- CADD 22.80
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available