M35L (p.Met35Leu) variant of IRF8 (Interferon regulatory factor 8)
M35L (p.Met35Leu) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
M35L (p.Met35Leu) variant details
- p.Met35Leu
- gnomAD 16-85903118-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.40
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.32
- Population evidence available
- Structural context available
- Literature evidence available