M22K (p.Met22Lys) variant of IRF8 (Interferon regulatory factor 8)
M22K (p.Met22Lys) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
M22K (p.Met22Lys) variant details
- p.Met22Lys
- ExAC rs751261768
- TOPMed rs751261768
- gnomAD rs751261768
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.42
- CADD 19.60
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available