K79M (p.Lys79Met) variant of IRF8 (Interferon regulatory factor 8)
K79M (p.Lys79Met) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
K79M (p.Lys79Met) variant details
- p.Lys79Met
- gnomAD 16-85909051-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.849
- REVEL 0.98
- CADD 29.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available