K64E (p.Lys64Glu) variant of IRF8 (Interferon regulatory factor 8)
K64E (p.Lys64Glu) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
K64E (p.Lys64Glu) variant details
- p.Lys64Glu
- gnomAD 16-85909005-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.823
- REVEL 0.94
- CADD 29.80
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available