I27I (p.Ile27Ile) variant of IRF8 (Interferon regulatory factor 8)
I27I (p.Ile27Ile) in IRF8 (Interferon regulatory factor 8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
I27I (p.Ile27Ile) variant details
- p.Ile27Ile
- rs749700728
- gnomAD 16-85903096-T-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.101
- CADD 2.87
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available
- Literature evidence available