G70W (p.Gly70Trp) variant of IRF8 (Interferon regulatory factor 8)
G70W (p.Gly70Trp) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.88 / 1. The record also includes population frequency data and structural context.
G70W (p.Gly70Trp) variant details
- p.Gly70Trp
- ExAC rs780120102
- gnomAD rs780120102
- Missense
- Variant Prioritization Score for Impact Estimate 0.877
- REVEL 0.91
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available