G44S (p.Gly44Ser) variant of IRF8 (Interferon regulatory factor 8)

G44S (p.Gly44Ser) in IRF8 (Interferon regulatory factor 8) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Immunodeficiency 32B; Mendelian susceptibility to mycobacterial diseases due to. The record also includes structural context.

G44S (p.Gly44Ser) variant details