F67L (p.Phe67Leu) variant of IRF8 (Interferon regulatory factor 8)
F67L (p.Phe67Leu) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
F67L (p.Phe67Leu) variant details
- p.Phe67Leu
- ExAC rs746153058
- Missense
- Variant Prioritization Score for Impact Estimate 0.523
- REVEL 0.61
- CADD 22.80
- PolyPhen-2 0.32
- SIFT 0.01
- Population evidence available
- Structural context available