F36L (p.Phe36Leu) variant of IRF8 (Interferon regulatory factor 8)
F36L (p.Phe36Leu) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data, published literature, and structural context.
F36L (p.Phe36Leu) variant details
- p.Phe36Leu
- gnomAD 16-85903121-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.841
- REVEL 0.96
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available