D71Y (p.Asp71Tyr) variant of IRF8 (Interferon regulatory factor 8)
D71Y (p.Asp71Tyr) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
D71Y (p.Asp71Tyr) variant details
- p.Asp71Tyr
- gnomAD 16-85909026-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.866
- REVEL 0.91
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available