C2Y (p.Cys2Tyr) variant of IRF8 (Interferon regulatory factor 8)
C2Y (p.Cys2Tyr) in IRF8 (Interferon regulatory factor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
C2Y (p.Cys2Tyr) variant details
- p.Cys2Tyr
- gnomAD 16-85903020-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- REVEL 0.52
- CADD 27.00
- PolyPhen-2 0.80
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available