W27L (p.Trp27Leu) variant of IRF4 (Interferon regulatory factor 4)
W27L (p.Trp27Leu) in IRF4 (Interferon regulatory factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data, published literature, and structural context.
W27L (p.Trp27Leu) variant details
- p.Trp27Leu
- gnomAD 6-393232-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.901
- REVEL 0.96
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.88
- Population evidence available
- Structural context available
- Literature evidence available